8:3 For what the law couldn’t do, in that it was weak through the flesh, God did, sending his own Son in the likeness of sinful flesh and for sin, he condemned sin in the flesh,
Muslims think that Jesus' title of 'Son' means God entered into a biological relationship with Mary, yet in the OT 'Son' is a title rooted in kingship and deity.
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The Uniqueness of Jesus in the Qur'an and the Bible, John Gilchrist
Son of God: what do the Qur'an and the Bible say?, CCI